FIELD: organic chemistry. SUBSTANCE: invention proposes new method of synthesis of 1-hydroxyadamantane-4-one (immunostimulating medicinal agent "Kemantan") by oxidation of adamantanone with a mixture of concentrated sulfuric and nitric acids in the presence of catalysts. The used catalysts are metal oxides of transient valency and alkaline metal nitrites. Formed chelate compounds were decomposed by boiling in the presence of inert carriers. EFFECT: increased yield, efficiency and quality of the end product. 3 cl
| Title | Year | Author | Number |
|---|---|---|---|
| 1-HYDROXYADAMANTANON-4-ONE PREPARATION METHOD | 2006 |
|
RU2319688C1 |
| METHOD OF SYNTHESIS OF ADAMANTANE-2-ONE | 1994 |
|
RU2109727C1 |
| METHOD OF OBTAINING 1-HYDROXYADAMANTHAN-4-ON | 2007 |
|
RU2342358C2 |
| METHOD OF PRODUCING 1-HYDROXY-4-ADAMANTANONE | 2014 |
|
RU2557249C1 |
| METHOD OF OBTAINING 1-HYDROXYADAMANTAN-4-ONE (KEMANTANE) | 2012 |
|
RU2507191C1 |
| METHOD OF PRODUCING 1-HYDROXYADAMANTAN-4-ONE | 2011 |
|
RU2491270C2 |
| METHOD OF PREPARING 1-HYDROXYADAMANTANE | 1997 |
|
RU2125037C1 |
| METHOD OF PREPARING 1-HYDROXY-4-AMINO- OR 4-N-SUBSTITUTED ADAMANTANES | 0 |
|
SU740752A1 |
| HYDROXY COMPOUNDS DI-(ADAMANTYL AMINE POSSESSING ANTICATALEPTIC ACTIVITY | 1978 |
|
SU731714A1 |
| METHOD OF SYNTHESIS OF N-(4-BROMOPHENYL)-N-(2-ADAMANTYL)AMINE | 1988 |
|
RU1601978C |
