FIELD: medicine, pharmacology. SUBSTANCE: method deals with pharmaceutical composition that contains N-[4-[5-(cyclopentyloxycarbonyl) amino-1-methylindol-3-il-methyl] -3-methoxybenzoil] -2-methylbenzolsulfonamide, polyvinylpyrrolidone and carrier at a certain weight ratio. The given composition is obtained by mixing and drying its ingredients. Physical form of active substance is characterized by an intake maximum at 1690, 1530, 1490, 1420, 1155, 1060, 862 and 550 cmcm-1. The given composition is considered to be an antagonist of leukotriens, it is stable and possesses high pharmaceutical activity. EFFECT: higher efficiency. 5 cl, 7 cl, 3 tbl
Title |
Year |
Author |
Number |
CRYSTALLINE FORM OF N-[4-[5(CYCLOPENTYLOXYCARBONYL)-AMINO-1-METHYL-INDOLE-3-YLMETHYL]-3- METHOXYBENZOYL]-2-METHYLBENZENE SULFONE AMIDE POSSESSING ACTIVITY AS ANTAGONIST OF LEUCOTRIENES |
1991 |
- Martin Pol Ehdvards[Gb]
- Dzhon Dehvid Shervud[Gb]
|
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PHYSICAL FOAM OF (R)-3-METHOXY-4-1-METHYL-5- 2-METHYL- 4,4,4-TRIFLUOROBUTYLCARBAMOYL) INDOL-3-YLMETHYL-N-(2- METHYLPHENYL-SULPHONYL)BENZAMIDE, PHARMACEUTICAL COMPOSITION HAVING PROPERTIES OF LEUCOTRIENE ANTAGONIST |
1992 |
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METHOD FOR PRODUCTION OF 3-ALKYLATED INDOLE AND (2-NITROPHENYL)-ACETALDEHYDE |
1991 |
- Robert Toms Dzhehkobs[Gb]
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1990 |
- Rodni Brajan Khargrivs[Gb]
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- Bernard Dzhozef Makloglin[Gb]
- Stjuart Dennet Millz[Gb]
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4-[2-(2-HYDROXY-2-PHENYLETHYLAMINO)ETHOXY]-PHENYLACETIC ACID OR ITS BIOPRECURSOR OR PHARMACEUTICALLY ACCEPTABLE SALT, METHOD OF ITS SYNTHESIS, COMPOSITION BASED ON THEREOF |
1992 |
- Brajan Roj Khollouehj[Gb]
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