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2 544 856

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(51)

IPC

C07D471/04(2006-01-01)

A61K31/4375(2006-01-01)

A61P25/28(2006-01-01)

(21) (22)

Application

2008102993/04, 2008-01-25

(24)

Start date

2008-01-25

(22)

Actual filing date

2008-01-25

(45)

Published

2015-03-20

(72)

Inventor

Bachurin Sergej OlegovichKurkin Aleksandr Vital'EvichJurovskaja Marina AbramovnaZefirov Nikolaj Serafimovich

(73)

Holder

Bachurin Sergej OlegovichKurkin Aleksandr Vital'EvichJurovskaja Marina AbramovnaZefirov Nikolaj Serafimovich

NEW 2,3,4,5-TETRAHYDRO-1-PYRIDO[4,3-b]INDOLE DERIVATIVES AND METHODS FOR USING THEM Russian patent published in 2015 - IPC C07D471/04 A61K31/4375 A61P25/28

Abstract RU 2544856 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: given invention refers to new 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole derivatives, which can be used for modulating histamine receptors in individuals or for treating neurodegenerative diseases. The above derivatives have formula , wherein R¹ is specified in an alkyl, substituted alkoxy or phenyl, and aralalkyl; R² is specified in an alkyl, C₆-C₁₄-aryl optionally substituted by 1 to 5 substitutes specified in alkoxy and alkyl; R³ is an alkyl; and R⁴ is an alkyl.

EFFECT: presented are the new compounds effective as histamine receptor modulators, and a based pharmaceutical composition.

20 cl, 1 tbl, 1 ex

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RU 2 544 856 C2

Authors

Bachurin Sergej Olegovich

Kurkin Aleksandr Vital'Evich

Jurovskaja Marina Abramovna

Zefirov Nikolaj Serafimovich

Dates

2015-03-20—Published

2008-01-25—Filed