METHOD FOR DIAGNOSING GENERALIZED PICTURE OF MALIGNANT NEOPLASMS IN ONCOLOGIC CASES Russian patent published in 1998 - IPC

Abstract RU 2107294 C1

FIELD: medicine; oncology. SUBSTANCE: patient's peripheral blood is subjected to analysis in order to determine following parameters: total leukocyte number (x109l), percentages of lymphocytes, T-lymphocytes, monocytes, neutrophil-nuclear leukocytes in blood formula; absolute number of T- and B-lymphocytes (x109l), of segment-nuclear leukocytes (x109l), O-cells, T-early, sedimentless, restored, stable, theophylline-sensitive and theophylline-resistant lymphocytes; circulating blood volume. Patient's blood sample is also subjected to spontaneous HCT test and analyzed for immunoglobulins A and M concentrations. Parameters thus-obtained are used to calculate total populations of T-, and B-lymphocytes, O-cells, populations of T-early, sedimentless, restored, stable, theophylline- sensitive and theophylline-resistant lymphocytes using formulae Ntot = N lymphocytes or O-cells x CBV 9, i.e. circulating blood volume). Ratio indices are determined of total populations of immunocompetent cells as related to average tumor diameter (D) using specific formulae, and diagnostic immunocompetent indices. If three or more positive index values indicative of relationships of total populations of immunocompetent cells to average tumor diameter, and if diagnostic indices are positive in relation to threshold level value, oncologist diagnoses generalized tumescent process case. However, if these positive index values are obtained in number of two and less, no generalized process is diagnosed. EFFECT: higher degree of accuracy. 2 tbl

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RU 2 107 294 C1

Authors

Kshivets Oleg Mikhajlovich

Dates

1998-03-20Published

1995-10-09Filed