AN AQUEOUS MEDICINAL COMPOSITION SHOWING CAPABILITY OF REVERSIBLE THERMOREGULATED GEL-FORMATION Russian patent published in 1998 - IPC

FIELD: pharmacy. SUBSTANCE: composition has pharmaceutically effective amount of medicinal or diagnostic agent and the following components, mas. /vol. %: methylcellulose containing methoxyl-groups at the range 26-33%, 0.2-2.1; citric acid, 1.2-2.3; polyethylene glycol (average molecular mass is 300-50000 Da), 0.5-13; and pharmaceutically acceptable agent for pH value control. Composition has pH from 3 to 10. Composition is a liquid before administration and forms gel at body temperature immediately after administration or use. Composition provides bioavailability of pharmaceutically effective component and maintains effect of medicinal agents for the long period. Composition can be used in ophthalmology, dermatology and for body cavity treatment. EFFECT: enhanced effectiveness of composition. 12 cl, 2 dwg, 4 tbl