METHOD FOR DETERMINING IMMUNOGENIC ACTIVITY OF APHTHOUS FEVER VACCINE Russian patent published in 1998 - IPC

Abstract RU 2111764 C1

FIELD: medicine. SUBSTANCE: method involves applying complement-binding reaction using blood sera inactivated at 62-64 C and antigen. The blood sera are obtained at tenth-fourteenth day after rabbits immunization done. The antigen is extracted from complex mixture by applying chloroform or carbon tetrachloride and diluted before setting complement-binding reaction to produce titer being twice as large as its permissible limit titer. EFFECT: enhanced accuracy and reliability of method.

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RU 2 111 764 C1

Authors

Kruglikov B.A.

Tarasenko T.Ja.

Salazhov E.L.

Gunenkov V.V.

Sukharev O.I.

Rad'Kov V.N.

Eremets V.I.

Dates

1998-05-27Published

1996-06-26Filed