METHOD OF TREATMENT OF HUMAN WITH IMMUNOSUPPRESSION AT SEPSIS Russian patent published in 1998 - IPC

Abstract RU 2115428 C1

FIELD: medicine, infectious diseases. SUBSTANCE: invention proposes the use of human interleukin-2 prepared from yeast Saccharomyces cerevisiae. Strain is deposited in All-Russian Collection of industrial microorganisms at N VKPM-U 791. Interleukin-2 is administrated at doses from 100 000 to 3 000 000 IU/24 h/1 m2 patient body surface. In contrast to other interleukins used for treatment of sepsis the proposed interleukin-2 shows stimulating effect on "resting" lymphocytes, induces production of interleukin-8 and tumor necrosis factor. Method can be used for treatment of severe states in human caused by infection and for correction of IMMUNOSUPPRESSION at sepsis in human also. EFFECT: enhanced effectiveness of treatment. 5 tbl

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RU 2 115 428 C1

Authors

Tsibin Ju.N.

Gromov M.I.

Pivovarova L.P.

Razumova N.K.

Tarelkina M.N.

Masijanskaja T.I.

Shirokov D.M.

Bubnova N.A.

Toneh R.V.

Shljapnikov S.A.

Smirnov M.N.

Khromov-Borisov N.N.

Dates

1998-07-20Published

1995-03-28Filed