IMIDAZOLE DERIVATIVES OR THEIR PHYSIOLOGICALLY ACCEPTABLE SALTS, METHOD OF THEIR SYNTHESIS, AGENT FOR BLOOD HYPERTENSION DECREASE AND PHARMACEUTICAL COMPOSITION FOR BLOOD PRESSURE DECREASE Russian patent published in 1998 - IPC

Abstract RU 2116300 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to the synthesis of imidazole derivatives containing biphenylsulphonylurea or biphenylsulphonylurethan side-chain of the formula (I): where R1 - ethyl; R2 - methyl; N - O; R3 - COOH and R4 - SO-2

-NH-CO-NH-CH3. These compounds are high-active antagonists of angiotensin-II-receptors. EFFECT: improved method of synthesis, enhanced effectiveness of compounds synthesized. 7 cl, 1 tbl, 10 ex

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RU 2 116 300 C1

Authors

Kholger Khajch

Rainer Khenning

Adal'Bert Vagner

Khermann Gerkhards

Rajnkhard Beker

Bernvard Shel'Kens

Dates

1998-07-27Published

1993-03-05Filed