PHARMACEUTICAL COMPOSITION CONTAINING ALKYLSULFONAMIDE AS 5-HT AGONIST FOR RECTAL ADMINISTRATION Russian patent published in 1998 - IPC

Abstract RU 2118527 C1

FIELD: medicine, pharmacy. SUBSTANCE: composition has an effective amount of 3-[2-(dimethylamino)etrhyl]-N-methyl-1H-indole-5-methanesulfonamide or N-methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-et-hanesulfonamide as a free base or pharmaceutically acceptable solvate and solid saturated bases at hydroxyl number above 15. Composition is made as a solid dosed form and used for rectal administration. Composition is used for treatment of patients with migraine and "histamine" headache. Composition shows improved absorption of drug by organism and rapid effect. EFFECT: enhanced effectiveness of composition. 9 cl, 2 dwg, 2 tbl, 10 ex

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RU 2 118 527 C1

Authors

Nadin Merle

Izabell' Rishar

Izabell' Tieleman

Dates

1998-09-10Published

1993-05-03Filed