CONJUGATE OF ANTIMELANOMA ANTIBODY AND CYTOTOXIC AGENT AND A METHOD OF MELANOMA INHIBITION Russian patent published in 1998 - IPC

Abstract RU 2119352 C1

FIELD: medicine, oncology. SUBSTANCE: conjugate of antimelanoma antibody and cytotoxic agent is a conjugate of monoclonal antibody ZME-018 to an antigen GP-240 of melanoma cancer cells. Conjugate has also toxins or cytocidal agents, or cytostatics as cytotoxic agent. Method of melanoma inhibition involves administration to mammal with melanoma a conjugate by parenteral route at the dose 0.1-10 mg/1 kg body mass. EFFECT: enhanced effectiveness of melanoma inhibition. 4 cl, 13 dwg, 1 tbl

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RU 2 119 352 C1

Authors

Majkl Dzh.Rozenbljum

Dates

1998-09-27Published

1991-04-19Filed