PHARMACEUTICAL COMPOSITION Russian patent published in 1998 - IPC

Abstract RU 2120304 C1

FIELD: pharmacy. SUBSTANCE: composition has at least one ligand showing a selective activity to RXR_s,-receptors and at least one the second ligand showing a selective activity to RAR-α,-receptors in pharmaceutically acceptable carrier. Composition is used as a modulating agent for proliferation and/or differentiation of cells HL-60, in part, for systemic treatment of patients with acute promyelocytic leukemia. Composition can be used at low doses without tolerance and adverse effects. EFFECT: enhanced effectiveness of composition. 7 cl, 4 dwg, 2 ex

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RU 2 120 304 C1

Authors

Serzh Mishel'

Kristin Katelino

Mari-Sesil' Lenuar-Vial'

Mishel' Demarshez

Dates

1998-10-20—Published

1995-07-26—Filed