PERHYDROISOINDOLE DERIVATIVES AND METHOD OF PREPARATION THEREOF Russian patent published in 1998 - IPC

FIELD: chemical industry. SUBSTANCE: present invention concerns perhydroisoindole derivatives of general formula (I) wherein R symbols are identical and are phenyl radicals substituted optionally by halogen or methyl in position 2 or 3, and R′ is phenyl substituted optionally in position 2 by alkyl or alkoxy containing 1 or 2 carbon atoms, R″ is fluorine or hydroxy, and R″′ is hydrogen or R″ and R″′ are hydroxy, or R″ forms bond with R″′, and R^o is hydrogen or protecting radical, and also salts thereof when they are present, and preparation thereof. Intermediate synthesis compounds for preparation of derivatives having antagonistic activity with respect to compound P. EFFECT: improved properties of the title compounds. 8 cl, 42 ex, 1 tbl