N-SUBSTITUTED 3-AZABICYCLO [3 Russian patent published in 1998 - IPC

Abstract RU 2120439 C1

2.0] HEPTANE DERIVATIVES AND PHYSIOLOGICALLY TOLERABLE ACID SALTS THEREOF. FIELD: medicine. SUBSTANCE: present invention describes 3- azabicyclo [3.2.0] heptane derivatives wherein R1 is phenyl substituted optionally by one or two halogen atoms, trifluoromethyl, hydroxy, alkoxy, amino, cyano or nitro; or thienyl; R2 is H or phenyl; n is integer of 1 to 4; A is hydrogen or -C(R3)(R4)-C6H4(R5),, NR6-CO-C6H4(R5) or -CH=CH2, R3-H,OH or phenyl optionally substituted by fluorine, chlorine or bromine; R4 is H; or R3 and R4 together are oxygen; R5 is hydrogen, chlorine, fluorine or bromine, hydroxy, alkyl or methoxy; R6 is hydrogen or methyl or salts thereof. Said salts have neuroleplic activity . EFFECT: improved properties of the title compounds. 2 cl, 64 ex, 1 tbl

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RU 2 120 439 C1

Authors

Gerd Shtajner

Lilian Unger

Bertol'D Bel'

Gans-Jurgen Teshendorf

Dates

1998-10-20Published

1993-12-09Filed