VACCINE SHOWING CAPABILITY TO CAUSE IMMUNE RESPONSE AGAINST THE SELF-IGE BODY, METHOD OF VACCINE PREPARING AND METHOD OF MAMMAL IMMUNIZATION AGAINST IGE-MEDIATED ALLERGIC RESPONSES Russian patent published in 1998 - IPC

FIELD: medicine, vaccines. SUBSTANCE: vaccine against IgE-mediated allergic responses has a protein containing the complete amino acid sequence of constant domains CH2-CH3 of IgE molecule chain or structurally stable unit of the indicated amino acid sequence. Protein is bound at random with one or more heterologic protein-carriers and has adjuvant possibly. Vaccine is administrated with adjuvant or without the latter to increase a concentration of endogenous anti-IgE antibodies in plasma of patient with allergy disease. In practice vaccine can be used against all types of IgE-mediated allergies since antibodies do not depend on antigenic specificity of IgE molecule but will decrease all IgE content in person in total. EFFECT: enhanced effectiveness of vaccine, improved method of preparing. 12 cl, 3 dwg