FIELD: medicine, vaccines. SUBSTANCE: invention represents vaccine conjugates, immunogenic polypeptides, nucleic acid molecules encoding immunogenic polypeptides, host-cells containing nucleic acid molecules encoding immunogenic polypeptides and methods for preparing vaccine conjugates and immunogenic polypeptides as well as nucleic acid molecules encoding immunogenic polypeptides. Except for, invention represents IgE-vaccine that induces response to "one's own" IgE in mammals. Invention provides reducing effects of IgE antibodies in mammal by decline of total and bound with receptor amount of IgE receptor in mammal. EFFECT: valuable properties of vaccine. 26 cl, 4 dwg, 10 ex
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