DERIVATIVES OF NAPHTHALENE AND DIHYDRONAPHTHALENE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF, METHODS OF TREATMENT AND INTERMEDIATES SUBSTANCES Russian patent published in 2001 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to novel derivatives of naphthalene or dihydronaphthalene of the formula (I) where R¹ means -OH or -O-(C₁-C₄-alkyl); R² means C₁-C₆-alkyl or C₅-C₇-cycloalkyl; X means -CH(OH)- or -CH₂-; M means CH₂-CH₂- or -CH= CH-; n = 2 or 3; R₃ means 1-piperidinyl or 1-pyrrolidinyl, or their pharmaceutically acceptable salts. Compounds of the formula (I) and their salts can be used for treatment of patients with estrogen-dependent pathological states and can be used in medicine. Invention describes pharmaceutical composition and methods of treatment of patients with estrogen-dependent pathological states. Invention describes intermediate substances as derivatives of naphthalene or dihydronaphthalene of the formula (II) where Y¹ means -OH or -OCH₃ also. EFFECT: new compounds indicated above, valuable medicinal properties. 19 cl, 3 tbl, 10 ex