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IPC

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Application

95119623/13, 1995-11-21

(22)

Actual filing date

1995-11-21

(45)

Published

1998-12-20

(72)

Inventor

Funtikova T.N.Tsygankova O.I.Eremenko E.I.Buravtseva N.P.

(73)

Holder

Stavropol'Skij Nauchno-Issledovatel'Skij Protivochumnyj Institut

METHOD OF SELECTION OF ANTHRAX VACCINE STRAIN CULTURES AND VACCINES PREPARED OF THEREOF Russian patent published in 1998 - IPC

Abstract RU 2123532 C1

FIELD: microbiology. SUBSTANCE: anthrax strain cultures are tested preliminary in vitro with respect to their capability to produce toxin in medium of capsule formation. Selected cultures at relative content of Tox+KOE 95-98% are subjected for selection on bilayer agar. Hemolysis zone-forming colonies (size is 2-8 mm) are isolated in 18-24 h. Selected cultures are tested and evaluated with respect to their culture-morpholigical properties, harmless and immunogenicity in vivo. Invention can be used for quality control of living anthrax vaccines. EFFECT: decreased time and cost for vaccine strains, subcultures and ready vaccines testing. 6 tbl, 6 ex

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RU 2 123 532 C1

Authors

Funtikova T.N.

Tsygankova O.I.

Eremenko E.I.

Buravtseva N.P.

Dates

1998-12-20—Published

1995-11-21—Filed

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