NEUTRAL LIPIDS FROM JOB'S TEARS GRAINS NLKY, METHOD OF THEIR PREPARING, COMPOSITION BASED ON THEREOF, NEUTRAL LIPIDS FOR USE AS A DRUG Russian patent published in 1998 - IPC

Abstract RU 2123853 C1

FIELD: medicine, biotechnology. SUBSTANCE: invention relates to development of method for preparing neutral lipids exhibiting high activity and sufficient purity degree for intravenous administration and composition based on thereof for oral, intravenous and intraarterial administration. Neutral lipids isolated from Job's tears grains are triglycerides, diglycerides, monoglycerids and fatty acid alkyl ester. Method of preparing involves an extraction of Job's tears grains with an organic solvent, alkaline saponification, neutralization of obtained emulsion with acetone, deemulsification with acetone and purification of acetone fraction by extraction of the end product with an organic solvent. A pharmaceutical composition consists of neutral lipids at amount 2.5-25 g and pharmaceutically acceptable additions and shows antitumor and immunostimulating effects. EFFECT: simplified method, decreased cost and toxicity of chemotherapeutic effect, safety of composition. 9 cl, 9 ex, 5 dwg

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RU 2 123 853 C1

Authors

Da Peng Li

Dates

1998-12-27Published

1993-09-15Filed