PYRANOQUINOLINE DERIVATIVES, PROCESS FOR PREPARING THEREOF, AND PHARMACEUTICAL COMPOSITION Russian patent published in 1999 - IPC

FIELD: pharmaceutical compounds, preparation and use thereof. SUBSTANCE: present invention describes pyranoquinoline derivatives of general formula I: wherein R¹ is phenyl optionally substituted by nitro, halogen atom, C_1-4-alkoxy, trifluoromethyl; R² is nitrile group; R³ is NR⁸R⁹ wherein R⁸ and R⁹ are H or C_1-4-alkyl; P-pyridine ring condensed with benzopyran ring in three forms of a-c structures. Compounds of formula I have antiproliferating effect on cell division and are useful for treating diseases where excessive cell growth or enzyme isolation is important aspect of pathology. EFFECT: improved properties of the pharmaceutical composition. 7 cl, 2 dwg, 8 ex, 1 tbl