VITAMIN D ANALOGS, PROCESS FOR PREPARATION THEREOF, INTERMEDIATE COMPOSITION, AND METHOD FOR SUPPRESSING MORBID STATES Russian patent published in 1999 - IPC

FIELD: medicine. SUBSTANCE: present invention describes compounds of formula (I): wherein X is hydroxy; R¹ and R² are the same or different and are methyl, ethyl or trifluoromethyl; Q is singly bond or Q is (CH₂)_n, wherein n is 0.1-4, and m is 0 or 1. Compounds have antiinflammatory and immunomodulating activity and are capable of inducing differentiation and inhibition of undesired proliferation of some cells. The present invention also describes preparation process, intermediate compound for preparing compound of formula (I) and pharmaceutical composition having antiproliferating activity and method for suppressing morbid states characterized by pathologic cell differentiation and proliferation such as cancer and psoriasis using compounds of formula (I). EFFECT: improved properties of the pharmaceutical composition and more efficient suppression method. 12 cl, 6 dwg, 20 ex, 1 tbl