FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to stereoisomeric forms of itraconazole (X is Cl) and superconazole (X is F) that can be presented as a formula cis-(I) 
, their pharmaceutically acceptable acid-additive salt forms, methods of synthesis of the above indicated stereoisomeric forms, their complexes with derivatives of cyclodextrin and a pharmaceutical composition containing the above indicated complexes exhibiting antifungal activity. EFFECT: improved method of synthesis, enhanced antifungal activity. 8 cl
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0 |
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SU703020A3 |
