AMINO ACID ESTERS, METHODS OF THEIR SYNTHESIS, INTERMEDIATE COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHOD OF ITS PREPARING Russian patent published in 2003 - IPC

FIELD: organic chemistry, amino acids, pharmacy. SUBSTANCE: invention describes ester of the general formula (I) , its N-oxide form, pharmaceutically acceptable additive salt or its stoichiometrically isomeric form where A-B- form bivalent radical of the formula: -N=CH- (a); -CH=N- (b) where one hydrogen atom in radicals (a) and (b) can be substituted with C_1-6-alkyl radical; L means acyl moiety of amino acid; D means radical of the formula or where X means N atom; R¹ means halogen atom; R² means hydrogen or halogen atom. Invention describes also methods of synthesis of compounds of the formula (I), pure enantiomeric form of intermediate compound, enantiomeric mixture of intermediate substances, pharmaceutical composition exhibiting antifungal activity of wide spectrum of effect and method of pharmaceutical composition preparing. Invention provides synthesis of new compounds eliciting useful biological properties. EFFECT: improved methods of synthesis and preparing, valuable medicinal and biological properties of compounds. 18 cl, 10 tbl