AMINOCARBOXYLIC ACID AMIDES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION Russian patent published in 1999 - IPC

Abstract RU 2134683 C1

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to aminocarboxylic acid amides of the formula (I) R1(R2)N-CO-(CH2)n-N(R3)-(CH2)m-N(R4)R5 (I), where R1,R2 - H, C1-8-alkyl, C3-8-cycloalkyl, phenyl or phenylalkyl possibly substituted with alkyl, alkoxyl, halogen atom, cyano-, nitro- CF3 or acylamino-group; or R1-N-R2 means morpholine, piperidine or the group (a) or (b) ; R3 is CO-R7 or O2S-C6H4-R8 (values of other radicals see p. 1 of the invention claim), their physiologically acceptable salts and pharmaceutical compositions on their base as new antiarrhythmic agents. EFFECT: new compounds showing antiarrhythmic properties. 5 cl, 3 tbl, 30 ex

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RU 2 134 683 C1

Authors

Vol'Fgang Zauer

Rudol'F Shindler

Karla Rjuger

Khildegard Poppe

Degenkhard Marks

Reni Barch

Kaverina N.V.(Ru)

Seredenin S.B.(Ru)

Lyskovtsev V.V.(Ru)

Likhosherstov A.M.(Ru)

Borisenko S.A.(Ru)

Kryzhanovskij S.A.(Ru)

Dates

1999-08-20Published

1994-11-12Filed