FIELD: chemical industry. SUBSTANCE: described is method of preparing N-acyl--amino acids of general formula: α wherein α are as defined in claim 1. Carboxylic acid amide of general formula III wherein R1,R2,R3 are as defined above, is reacted with aldehyde of formula R1 and R2 in the presence of solvent and acid to form acyl-amino-methyl of formula III. After adding cobalt carbonyl catalyst, this compound is carbonylated at temperature of 20-150 C and CO pressure of 1-150 bar. EFFECT: desired products having high yield and purity, method is industrially applicable. 10 ex, 1 tbl
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Authors
Dates
1999-11-10—Published
1995-04-28—Filed