FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel derivatives of glycopeptide of the general formula (I) 
where radical values are given in p. 1 of the invention claim. Compounds are new members of glycopeptide antibiotics group. They elicit the broad activity against gram-positive microorganisms and improved antibacterial activity against isolates showing resistance to vancomycin. Invention describes also the method of synthesis of the above indicated compounds and a pharmaceutical composition based on compounds of the formula (I). EFFECT: improved method of synthesis, enhanced antibacterial properties. 19 cl, 7 tbl, 13 ex
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