PHARMACEUTICAL COMPOSITION FOR MEDICINAL PUPIL OF EYE MYDRIASIS IN OPHTHALMOLOGY Russian patent published in 2000 - IPC

Abstract RU 2148404 C1

FIELD: medicine, ophthalmology. SUBSTANCE: pharmaceutical composition for pupil of eye mydriasis containing mydriatic agent has additionally heparin and viscoelastic at the following ratio of components, wt.-%: mydriatic agent 0.005-1.0; heparin 5-500 U/ml and viscoelastic - the rest and composition can contain topical anesthetic at concentration 0.01-1.0%. The following substances can be used as viscoelastic, %: sodium hyaluronate 0.1-0.3 and/or chondroitin sulfate 0.1-6.0, and/or water-soluble derivatives of cellulose in isotonic saline solution at pH 7.0-7.5 0.1-6.0, or alkyl-, and/or carboxyalkyl-, and/or hydroxyalkyl-derivatives of cellulose 0.21-6.0; sodium chloride 0.85-0.95; sodium dihydrogen phosphate 0.0025-0.0040; sodium hydrogen phosphate 0.0115-0.0135; glycoseaminoglycans 0.0051-0.080 and purified water - the rest. Invention can be used in cavity eye operations (cataract extraction [phacoemulsification] in combination with implantation of artificial optical lens, vitreoectomy and other vitreoretinal operations), for intrachamber administration, providing and maintenance of mydriasis. EFFECT: decreased complications, broadened arsenal of agents. 5 cl, 7 ex

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RU 2 148 404 C1

Authors

Fedorov S.N.

Maljugin B.Eh.

Bagrov S.N.

Maklakova I.A.

Verzin A.A.

Dates

2000-05-10Published

1999-07-08Filed