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Application

99101614/14, 1999-01-28

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Start date

1999-01-28

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Actual filing date

1999-01-28

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Published

2000-05-27

(72)

Inventor

Erichev V.P.Koval'Chuk L.V.Gankovskaja L.V.Vasilenkova L.V.Klebanov G.I.Dolgina E.N.Nikankina L.V.

(73)

Holder

Moskovskij Nauchno-Issledovatel'Skij Institut Glaznykh Boleznej Im. Gel'Mgol'Tsa

METHOD FOR EVALUATING ANTI-INFLAMMATORY ACTIVITY OF CYTOKINETIC AGENTS Russian patent published in 2000 - IPC

Abstract RU 2150113 C1

FIELD: medicine. SUBSTANCE: method involves evaluating free radicals inhibition activity shown by cytokinetic agents in model system hemoglobin- hydrogen peroxide-luminol. To do it, chemoluminescence intensity coefficient is determined in hemoglobin-hydrogen peroxide-luminol model system. Then, a cytokinetic agent is added to the model system in the amount of 0.1-100 ng and the chemoluminescence intensity coefficient is determined for the second time. The value becoming 50% or more lower relative to the initial level, the cytokinetic agent activity is to be assessed as anti-inflammatory. EFFECT: reliable and accurate method. 2 cl, 3 dwg

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RU 2 150 113 C1

Authors

Erichev V.P.

Koval'Chuk L.V.

Gankovskaja L.V.

Vasilenkova L.V.

Klebanov G.I.

Dolgina E.N.

Nikankina L.V.

Dates

2000-05-27—Published

1999-01-28—Filed

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