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Application

97108814/14, 1997-05-22

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Start date

1997-05-22

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Actual filing date

1997-05-22

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Published

2000-07-10

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Inventor

Sandakhchiev L.S.Kolokol'Tsova T.D.Kostina N.E.Nechaeva E.A.Jurchenko N.D.Ryzhikov A.B.Varaksin N.A.Rjabicheva T.G.Poryvaev V.D.

(73)

Holder

Gosudarstvennyj Nauchnyj Tsentr Virusologii I Biotekhnologii

TABLETTED FORM OF RECOMBINANT HUMAN ERYTHROPOIETIN FOR ORAL USE AND METHOD OF ITS PREPARING Russian patent published in 2000 - IPC

Abstract RU 2152206 C1

FIELD: medicine. SUBSTANCE: invention relates to production of medicinal-biological preparations, in part, to oral form of recombinant human erythropoietin used for treatment of different forms of anemia. Form is prepared by mixing erythropoietin with stabilizing additions taken at the definite ratios at erythropoietin dose is 100-2 000 U/tablet followed by lyophilization. Lyophilized erythropoietin is mixed with lactose, calcium sterate and vanillin and pressed to make tablets which are covered then by acid-resistant envelope. Obtained form is more easily for intake. EFFECT: improved properties, increased stability at storage. 2 cl, 2 tbl

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RU 2 152 206 C1

Authors

Sandakhchiev L.S.

Kolokol'Tsova T.D.

Kostina N.E.

Nechaeva E.A.

Jurchenko N.D.

Ryzhikov A.B.

Varaksin N.A.

Rjabicheva T.G.

Poryvaev V.D.

Dates

2000-07-10—Published

1997-05-22—Filed

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