METHOD OF TREATMENT OF CHILDREN WITH DIPHTHERIA POLYNEUROPATHY Russian patent published in 2000 - IPC

FIELD: medicine, pediatry. SUBSTANCE: method involves carrying out the complex therapy depending on time of appearance of neurological complication symptoms and their form. In early neuropathy (from 3-d to 15-th day of disease) in patients with subtoxic and chronic form of diphtheria 2-5 seances of hemosorption are carried out in break for 12-24 h and then pentoxyphyllin (4-10 mg/kg body mass per 24 h) and prednisolone (5 mg/kg body mass per 24 h for 5-7 days) are prescribed. In late generalized forms of disease appearing from 16-th to 60-th day in period of rise of symptoms plasmapheresis is carried out (2-3 seances in break for 24-36 h). In amyotrophic form in period of stabilization of paresis strychnine (dose is 1 ml in dilution 1:10000 per one year of life, 3 times per 24 h) and epaden (2 drops per one year of life, 3 times per a day in combination with vitamin E) are prescribed orally. EFFECT: decreased lethality, improved prognosis.