FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel derivatives of phenyloxoalkyl-(4- -piperidinyl)-benzoate of the formula (I) 
, their N-oxide forms, salts and sterically isomeric forms where R1 is halogen atom; R2 is hydrogen atom; R3 is C1-6-alkyl or R2 and R3 form in common bivalent radical of the formula -(CH2)2- or -(CH2)3-; Alk is C1-6-alkanediyl; R4 is hydrogen atom or C1-6-alkoxy-group; R5, R6, R7 are hydrogen, halogen atom, C1-6-alkyl, C1-6-alkoxy-group or R5 and R6 taken in common form bivalent radical of the formula -NR8-C(O)-NR9- or -NH-C(NH-R10)=N where R8 and R9 are hydrogen atom, C1-6-alkyl; R10 is hydrogen atom, C1-6-alkylcarbonyl, C1-6-alkylhydroxycarbonyl. Compounds of the formula (I) show activity stimulating gastrointestinal peristalsis and can be used in medicine. EFFECT: new compounds indicated above, valuable medicinal properties. 11 cl, 1 tbl, 14 ex
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Year |
Author |
Number |
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|
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