ACYL DERIVATIVES OF GUANOSINE, INOSINE, XANTHOSINE, DEOXY-INOSINE, DEOXYGUANOSINE, INOSINE-2',3'-(ACYCLIC)-DIALCOHOL OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, HEMOPOIESIS-STIMULATING PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF CYTOPENIA Russian patent published in 2000 - IPC

Abstract RU 2158269 C2

FIELD: organic chemistry, heterocyclic compounds, pharmacy. SUBSTANCE: invention relates to the novel acyl derivatives of guanosine of the formula (I) , inosine of the formula (II) , xanthosine of the formula (III) , deoxyinosine of the formula (IV) , deoxyguanosine of the formula (V) , inosine-2', 3'-(acyclic)-dialcohol of the formula (VI) or their pharmaceutically acceptable salts. Values of radicals RA,RB,RC,RD, Y, Q and Z are given in corresponding points of the invention claim. Invention describes a pharmaceutical composition stimulating hemopoiesis and containing derivatives of guanosine or inosine or their salts as an active agent. Invention proposes also method of treatment of animals with cytopenia by administration of indicated compounds in effective doses. Invention can be used in medicinal practice and therapy in hemopoiesis disorders. EFFECT: compounds indicated above, valuable medicinal properties. 17 cl, 68 dwg, 53 ex

Similar patents RU2158269C2

Title Year Author Number
COMPOSITION, METHOD OF HEALING STIMULATION 1989
  • Rejd Varren Fon Borstel'
  • Majkl Kevin Bejmat
RU2115410C1
METHOD FOR TREATING SEPSIS AND INFLAMMATIONS DUE TO OXYPURINE NUCLEOSIDES 1995
  • Fon Borstel Rejd V.
  • Bamat Mikhael K.
  • Khiltbrand Bredli M.
  • Butler Dzhejms S.
  • Shirali Shiam
RU2203669C2
NOVEL PRODRUGS OF NUCLEIC ACIDS AND THEIR APPLICATION METHODS 2010
RU2612521C2
METHODS OF TREATING LEUKOPENIA AND THROMBOCYTOPENIA 2015
  • Khan En-Khe
  • Chon Sekho
  • Son Ki-Yun
  • Kim Men-Khvan
  • Kim Che Khva
RU2702122C2
LEUKOTRIENE A4-HYDROLASE INHIBITORS 2014
  • Gilford Uilyam
  • Dejvi Devid
RU2690489C2
LEUKOTRIENE A4-HYDROLASE INHIBITORS 2014
  • Gilford Uilyam
RU2696559C2
PHARMACEUTICAL COMPOSITIONS WITH REDUCED RELEASE OF PHENOL OPIOIDS 2009
  • Dzhenkins Tomas Eh.
  • Serudzhi Dzhuli D.
  • Rehj Dzhonatan V.
RU2562583C2
LACTAM COMPOUNDS AND THEIR PHARMACEUTICAL USING 2001
  • Jino Jukio
  • Ikenoue Takao
  • Kondo Nobuo
  • Matsueda Khirojuki
  • Khatanaka Tosikhiro
  • Khirama Riusuke
  • Masuzava Joko
  • Okhta Fumio
  • Jamazaki Akijo
RU2287530C2
PHARMACEUTICAL COMPOSITIONS CONTAINING AGONIST OR ANTAGONIST OF ADENOSINE RECEPTOR 2000
  • Fishmehn Pnina
RU2239455C2
TAXOIDS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 1995
  • Ehrve Bushar
  • Zhan-Dominik Burza
  • Alan Kommerson
RU2144920C1

RU 2 158 269 C2

Authors

Rejd Uorren Fon Borstel

Majkl Kevin Behmat

Brehdli Mark Khiltbrehnd

Dzhejms Charl'Z Batler

Dates

2000-10-27Published

1992-02-05Filed