AROYLPIPERIDINE DERIVATIVES OR THEIR SALTS, PHARMACEUTICAL PREPARATION BASED ON THEM, AND METHOD OF PREPARATION THEREOF Russian patent published in 2000 - IPC

Abstract RU 2158731 C2

FIELD: biologically- active compounds. SUBSTANCE: invention provides novel aroylpiperidine derivatives with general formula I: (I), wherein X and Y represent, independently of each other, nitrogen atom or CH group and ring A is unsubstituted or substituted benzene ring, and their salts. Compounds manifest antagonistic activity toward the substance P and can be used in treatment of migraines and central nervous system disorders such as phobias, vomiting, schizophrenia, and depression. EFFECT: increased assortment of neuroleptics. 4 cl, 10 ex

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RU 2 158 731 C2

Authors

D-R Sil'Vio Ofner

D-R Sim Jakob Finstra

D-R Val'Ter Shilling

Dates

2000-11-10Published

1995-10-13Filed