10-AMINOALIPHATYLDIBENZ [b, f] OXEPINES, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION Russian patent published in 2000 - IPC

Abstract RU 2160734 C2

FIELD: pharmaceutical industry. SUBSTANCE: described are new compounds, more specifically 10-aminoaliphatyldibenz [b, f] oxepines of formula I: wherein alk is C2-C7 alkenylamino, C2-C7 alkynylamino, N-C2-C7 alkenyl-N-C1-C4 alkylamino, N-C2-C7 alkynyl N-C1-C4 alkylamino, and R1, R2, R3 and R4 are independently hydrogen, C1-C4 alkyl, C1-C4 alkoxy, halogen having atomic number up to 35 or trifluoromethyl, and salts thereof. Said compounds are useful as drugs of antineurodegenerative activity. Also described are methods of preparing compounds of formula and pharmaceutical composition based thereon. EFFECT: improved properties of the title compounds. 11 c, 29 ex

Similar patents RU2160734C2

Title Year Author Number
DERIVATIVES OF N-PHENYL-2-PYRIMIDINEAMINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION ON SAID AND METHOD OF INHIBITION (TREATMENT) OF TUMOR 1994
  • Jurg Tsimmermann
RU2135491C1
DERIVATIVES OF AMINOPHOSPHONIC AND AMINOPHOSPHINIC ACIDS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF 1997
  • P'Er Aklin
  • Khans All'Gaer
  • Iv Oberson
  • Sil'Vio Ofner
  • Sim Jakob Veenstra
RU2181362C2
PHARMACEUTICAL COMPOSITION (VARIANTS), DERIVATIVES OF 3,5-DIPHENYL-1,2,4-TRIAZOLES COMPRISING THEREOF 1997
  • Lattmann Rene
  • Aklin P'Er
RU2208010C2
TYROSINE KINASE INHIBITORS 2008
  • Brajtenshtajn Verner
  • Fjure Paskal'
  • Dzhejkob Sandra
  • Manli Pol Uill'Jam
RU2445309C2
1,2,4-SUBSTITUTED PIPERIDINES AND A METHOD OF THEIR SYNTHESIS, INTERMEDIUM COMPOUNDS OF PIPERIDONE AND A METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON NEW COMPOUNDS 1992
  • Val'Ter Shilling
  • Sil'Vio Ofner
  • Sim Dzh.Veenstra
RU2114829C1
DERIVATIVES OF QUINAZOLINE 2002
  • Berli Rene
  • Tommasi Ruben Alberto
  • Vajler Sven
  • Vidler Leo
RU2302244C2
DERIVATIVE OF α-AMINOHYDROXAMIC ACID, METHOD FOR ITS PREPARING AND PHARMACEUTICAL COMPOSITION 2000
  • Brajtenshtajn Verner
  • Khajaakava Kendzhi
  • Ivasaki Gendzhi
  • Kanazava Takanori
  • Kasaoka Tatsukhiko
  • Koizumi Shinichi
  • Matsunaga Shinichiro
  • Nakadzhima Motovo
  • Sakaki Junichi
RU2265592C2
2-CYANO-4-AMINOPYRIMIDINE COMPOUNDS WITH INHIBITOR ACTION ON CATHEPSIN K, PHARMACEUTICAL COMPOUND AND METHODS OF OBTAINING THEM (ALTERNATIVES) 2002
  • Al'Tman Ehva
  • Khajakava Kendzhi
  • Ivasaki Gendzhi
RU2326119C2
CYCLIC THIO-SUBSTITUTED DERIVATIVES OF ACYLAMINO ACID AMIDE AND METHOD OF THEIR SYNTHESIS 1998
  • Fink Sintija Anne
RU2193556C2
SUBSTITUTED DERIVATIVES OF BISPHENYL ESTER OF BUTYRIC ACID AS NEP INHIBITORS 2019
  • Godtfredsen, Sven Erik
  • Kagan, Mark
  • Liu, Yugang
  • Prashad, Mahavir
  • Wang, Zhaoyin
  • Zhu, Saijie
  • Chai, Yongshuai
RU2784522C2

RU 2 160 734 C2

Authors

Klaudia Betshart

Kaspar Tsimmermann

Dates

2000-12-20Published

1996-02-06Filed