FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to the novel derivatives of chromone of the general formula (I) where ring A is unsubstituted or monosubstituted with halogen atom and where ring B is unsubstituted or substituted with one-four substituents taken among the group consisting of lower alkyl, hydroxyl, lower alkoxyl, lower alkylthio-group or halogen atom and their salts. Invention describes also method of their synthesis and pharmaceutical composition based on compounds of the formula (I) that shows antagonistic effect with respect to neurokinin-1. EFFECT: new compounds indicated above, valuable medicinal properties. 12 cl, 7 ex
Title |
Year |
Author |
Number |
AROYLPIPERIDINE DERIVATIVES OR THEIR SALTS, PHARMACEUTICAL PREPARATION BASED ON THEM, AND METHOD OF PREPARATION THEREOF |
1995 |
- D-R Sil'Vio Ofner
- D-R Sim Jakob Finstra
- D-R Val'Ter Shilling
|
RU2158731C2 |
1,2,4-SUBSTITUTED PIPERIDINES AND A METHOD OF THEIR SYNTHESIS, INTERMEDIUM COMPOUNDS OF PIPERIDONE AND A METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON NEW COMPOUNDS |
1992 |
- Val'Ter Shilling
- Sil'Vio Ofner
- Sim Dzh.Veenstra
|
RU2114829C1 |
PHARMACEUTICAL COMPOSITION (VARIANTS), DERIVATIVES OF 3,5-DIPHENYL-1,2,4-TRIAZOLES COMPRISING THEREOF |
1997 |
|
RU2208010C2 |
DERIVATIVES OF AMINOPHOSPHONIC AND AMINOPHOSPHINIC ACIDS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITIONS BASED ON THEREOF |
1997 |
- P'Er Aklin
- Khans All'Gaer
- Iv Oberson
- Sil'Vio Ofner
- Sim Jakob Veenstra
|
RU2181362C2 |
ACYLAMINOALKENYLENEAMIDE DERIVATIVES, METHODS OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF |
1997 |
- Gershpakher Mark
- Fon Shprekher Andreas
- Makh Robert
- Roggo Sil'Vio
- Shtutts Shtefan
|
RU2185375C2 |
NEW PHARMACEUTICAL COMPOSITIONS |
1999 |
|
RU2240121C2 |
BENZOPYRANS, METHOD OF PREPARATION THEREOF, INTERMEDIATE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS |
1996 |
|
RU2160735C2 |
10-AMINOALIPHATYLDIBENZ [b, f] OXEPINES, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION |
1996 |
- Klaudia Betshart
- Kaspar Tsimmermann
|
RU2160734C2 |
CYCLIC THIO-SUBSTITUTED DERIVATIVES OF ACYLAMINO ACID AMIDE AND METHOD OF THEIR SYNTHESIS |
1998 |
|
RU2193556C2 |
AMIDES OF δ-AMINO-γ-HYDROXY-ω-ARYLALCANE ACID |
2004 |
- Behshlin Daniel' Kaspar
- Majbaum Jurgen Klaus
- Zell'Ner Khol'Ger
|
RU2413716C2 |