FIELD: analytical chemistry, more particularly synthesis of biologically active compounds. SUBSTANCE: method comprises reacting 2-thio-4-imino-6-oxopyrimidine or tautomeric form thereof or salt thereof with organic acid selected from HCOOH or CH3COOH at 40-150 C for 5-130 minutes at starting compound to organic acid molar ratio of 1:2.0-50. Method makes it possible to increase yield of the high quality product to 85%. EFFECT: more efficient preparation method. 6 ex, 1 tbl
| Title |
Year |
Author |
Number |
| METHOD OF SYNTHESIS OF THIOBARBITURIC ACID |
1994 |
|
RU2078080C1 |
| METHOD FOR OBTAINING ACYCLOXY-SUBSTITUTED BARBITURIC ACIDS |
2017 |
- Terentev Aleksandr Olegovich
- Vil Vera Andreevna
- Bityukov Oleg Vadimovich
- Gorlov Evgenij Sergeevich
|
RU2649146C1 |
| 5,5'-ARYLIDENE-BIS-BARBITURIC AND 5,5'-ARYLIDENE-BIS-2-THIOBARBITURIC) ACID SALTS AND 5,5'-ARYLIDENE-BIS-(2-THIOBARBITURIC) ACIDS SHOWING ANTIBACTERIAL, ANTIVIRAL, IMMUNOMODULATING AND ANTITUMOR EFFECT |
1997 |
|
RU2188195C2 |
| DRUG PREPARATION WITH ANTIVIRAL ACTIVITY (VERSIONS) |
2015 |
- Tets Viktor Veniaminovich
- Tets Georgij Viktorovich
- Krasnov Konstantin Andreevich
|
RU2595038C1 |
| METHOD FOR PREPARING DERIVATIVES OF THIOBARBITURIC ACID |
2000 |
- Urviler Bernkhard
- Rapol'D Tomas
- Passafaro Marko
|
RU2242467C2 |
| METHOD OF SYNTHESIS OF HEXAFLUOROBENZENE AND ITS MONO- AND DISUBSTITUTED DERIVATIVES |
1996 |
- Bil'Dinov I.K.
- Deev L.E.
- Nazarenko T.I.
- Podsevalov P.V.
|
RU2135453C1 |
| METHOD OF SYNTHESIS OF 1-(3-ALKOXY-2- CARBAMOYLHYDROXYPROPYL) -(1H,3H,5H) -PYRIMIDINE- 2,4,6-TRIONE AND DERIVATIVES OF (1H,3H,5H)- PYRIMIDINE-2,4,6- TRIONE |
1991 |
- Bernar Zigfrid[Fr]
- Indrzhikh Vakhta[Ch]
- Karel Val'Ter[Ch]
- Stefan Khugentobler[Ch]
|
RU2050353C1 |
| METHOD OF DETERMINATION OF MEDICATION PREPARATION-PYRIDIN DERIVATIVES |
0 |
- Bejsenbekov Alimkhan Sabekovich
|
SU941890A1 |
| METHOD OF SEPARATING SULFIDE COPPER-MOLYBDENUM PRODUCTS |
0 |
|
SU837310A3 |
| METHOD OF SYNTHESIS OF HEXAFLUOROBENZENE OR ITS MONO- OR DISUBSTITUTED DERIVATIVES |
1995 |
- Bil'Dinov Igor' Konstantinovich
- Deev Leonid Evgen'Evich
- Nazarenko Tat'Jana Ivanovna
- Podsevalov Pavel Viktorovich
|
RU2084437C1 |
