5,5'-ARYLIDENE-BIS-BARBITURIC AND 5,5'-ARYLIDENE-BIS-2-THIOBARBITURIC) ACID SALTS AND 5,5'-ARYLIDENE-BIS-(2-THIOBARBITURIC) ACIDS SHOWING ANTIBACTERIAL, ANTIVIRAL, IMMUNOMODULATING AND ANTITUMOR EFFECT Russian patent published in 2002 - IPC

FIELD: organic chemistry, medicine. SUBSTANCE: invention relates to novel 5,5'-arylidene-bis-barbituric and 5,5'- arylidene-bis-(2-thiobarbituric) acids salts and 5,5'-arylidene-bis-(2- thiobarbituric) acids of the general formula (I) showing an antibacterial, antiviral, immunomodulating and antitumor effect. In the general formula (I) X is taken among oxygen or sulfur atom; R¹ is taken among the group: hydrogen atom, nitro-group, alkoxy-group; R² is taken among the group: hydrogen atom, nitro-group, alkoxy-group, halogen atom; Cat^* is taken among the group including proton, pyridinium- or 2-hydroxyethylammonium cation. Compounds are preferable where: X is O; Cat⁺ is pyridinium; R¹ is H; R² is Cl (I); X is O; Cat⁺ is pyridinium; R′ is H; R² is NO₂ (II); X is O; Cat⁺ is NH₂CH₂CH₂OH; R¹ is H; R² is NO₂ (III); X is S; Cat⁺ is pyridinium; R¹ is H; R² is Cl (IV); X is S; Cat⁺ is pyridinium; R¹ is H; R² is OH (V); X is S; Cat⁺ is pyridinium; R¹ is NO₂; R² is H (VI); X is S; Cat⁺ is pyridinium; R′ = R² is MeO (VII); X is O; Cat⁺ is pyridinium; is H; R² is Br (VIII); X is O; Cat⁺ is H; R¹ is H; R² is Cl (IX); X is O; Cat⁺ is H⁺; R¹ is H; R² is NO₂ (X). EFFECT: new compounds indicated above, valuable medicinal properties. 11 cl, 8 tbl