FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes substituted imidazolidine-2,4-compounds of the general formula (I) 
where R1,R2,R3,R4 have values indicated in the invention claim. Compounds show antivasculitis effect and high immunomodulating activity that results to inhibition of release of tumor necrosis factor-α and interleukin-2. Invention relates to method of synthesis of these compounds also. EFFECT: improved method of synthesis, valuable medicinal properties. 12 cl, 5 tbl, 28 ex
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