PREPARATION OF CEPHOTAXIME AND SODIUM SALT OF CEPHOTAXIME Russian patent published in 2001 - IPC

Abstract RU 2169150 C2

FIELD: chemical industry. SUBSTANCE: described is method of preparing cephotaxime of formula I: by reacting compound of formula I: with compound of formula III; in acetone and optionally converting compound of formula I in the presence of source of sodium ions in admixture of acetone and water into sodium salt of cephotaxime in the form of rounded-off agglomerates with bulk density of 0.2-0.6 g/ml or in the from of needle-shaped crystals. EFFECT: high purity of cephotaxime and sodium salt thereof and also efficiency of process. 9 cl

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RU 2 169 150 C2

Authors

Makher Ingol'F

Vidshventer Gerkhard

Dates

2001-06-20Published

1995-12-22Filed