FIELD: organic chemistry, biochemistry, virology. SUBSTANCE: invention describes novel L-nucleosides of the general formula (I) where R is residue of uracil, thymine, cytosine or purine; R'' is hydrogen atom, acyl, alkyl, monophosphate, diphosphate or triphosphate or its pharmaceutically acceptable salts that show anti-HBV or anti- EBV activity. Invention describes also method of inhibition of HBV or EBV infection. EFFECT: new compounds indicated above, valuable antiviral properties. 13 cl, 20 dwg, 2 tbl, 5 ex
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