FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes compounds of the formula (I) 
and their salts with physiologically acceptable acids and their steroisomers where substituents have values given in the invention description. Invention describes also intermediate compounds of the formula (II) 
used for their synthesis. Synthesized compounds can be used for treatment of patients with diseases associated with coagulation blood system and for thrombosis prophylaxis also, for example, after surgery operations. EFFECT: valuable medicinal properties of compounds. 3 cl, 2 dwg, 253 ex
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