FIELD: veterinary medicine.
SUBSTANCE: invention relates to a new conjugate of a cell-binding agent and maitanzinoid, including a self-splitting peptide linker. Compositions and methods used for the inhibition of abnormal cell growth or treatment of a proliferative disorder in a mammal using compounds or conjugates according to this invention are also proposed.
EFFECT: obtaining compounds for the treatment of a proliferative disorder in mammals.
42 cl, 27 dwg, 5 tbl, 12 ex
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