CONJUGATE ANTIBODY-DERIVATIVE OF PYRROLOBENZODIAZEPINE Russian patent published in 2024 - IPC C07K16/00 C07K19/00 C07D519/00 A61K31/5513 A61K39/395 A61P35/00 

Abstract RU 2820928 C2

FIELD: chemistry.

SUBSTANCE: invention relates to biochemistry, particularly to an antibody-drug conjugate for treating and preventing cancer. Disclosed are a compound which is used to produce said conjugate; pharmaceutical composition containing said conjugate. Also disclosed is a method of treating a tumour using said conjugate.

EFFECT: invention makes it possible to effectively treat cancer.

66 cl, 2 tbl, 49 dwg, 154 ex

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RU 2 820 928 C2

Authors

Kharada, Naoia

Ota, Yusuke

Doi, Fuminao

Meguro, Masaki

Khayakava, Itiro

Asida, Sintszi

Masuda, Takesi

Nakada, Takasi

Ivamoto, Mitsukhiro

Kharada, Naoya

Terauti, Tomoko

Okatszima, Dajsuke

Nakamura, Kensuke

Utida, Khiroaki

Khamada, Khirofumi

Dates

2024-06-13Published

2018-09-28Filed