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2 173 146

(13)

C2

(51)

IPC

(21) (22)

Application

98102400/14, 1996-07-12

(24)

Start date

1996-07-12

(22)

Actual filing date

1996-07-12

(45)

Published

2001-09-10

(72)

Inventor

Dimehjo DzhonDiksit Dilip M.

(73)

Holder

Biokhim Farma Ink.

DERIVATIVES OF POLYCYCLIC ALKALOIDS AS ANTAGONISTS OF NMDA-RECEPTORS Russian patent published in 2001 - IPC

Abstract RU 2173146 C2

FIELD: natural compounds, alkaloids. SUBSTANCE: invention relates to novel polycyclic alkaloids that are able to bind or to be as antagonists of NMDA (N-methyl-D-aspartic acid) receptor complex or to protect neurons against degeneration induced by receptor of stimulatory amino acids by another manner. In another aspect invention relates to method of inhibition of activation of NMDA-receptors in mammals using new polycyclic alkaloids proposed by this invention. EFFECT: new compounds indicated above, valuable pharmacological properties. 3 cl, 3 dwg, 1 tbl, 17 ex

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RU 2 173 146 C2

Authors

Dimehjo Dzhon

Diksit Dilip M.

Dates

2001-09-10—Published

1996-07-12—Filed

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