SEMICARBAZONE COMPOUNDS, COMPOSITION Russian patent published in 2001 - IPC

FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes compounds of semi-carbazone of the formula (I) where R¹,R²,R³,R⁴ can be similar or different and mean halogen atom, C_1-9-alkyl, cyano-group, C_1-9-alkoxy-group or phenoxy-group; R⁵ means hydrogen atom or C_1-9-alkyl; X means oxygen or sulfur atom under condition that: a) if X is sulfur atom then at least one of radicals R¹ and R² is not hydrogen atom but other substitute or at least one of radicals R³ and R⁴ is fluorine atom, C_1-9-alkyl, cyano-group, C_1-9-alkoxy-group; b) if X means oxygen atom, R⁵ means hydrogen atom, methyl or ethyl and one of radicals R¹ and R² is chlorine atom then other radical of R¹ and R² is not hydrogen or chlorine atom or at least one radical of R³ and R⁴ is not hydrogen atom but other substitute; c) if X means oxygen atom, R⁵ means hydrogen atom, methyl or ethyl and one of radicals R¹ and R² is methoxy-group then other radical of R¹ and R² is not hydrogen atom or methoxy-group or at least one radical of R³ and R⁴ is not hydrogen atom and other is a substitute; d) if X means oxygen atom, R⁵ means hydrogen atom, methyl or ethyl and one of radicals R¹ and R² is methyl then other radical of R¹ and R² is not hydrogen atom or at least one radical of R³ and R⁴ is not hydrogen atom but other substitute and e) if X means oxygen atom, R⁵ means hydrogen atom, methyl or ethyl and if both radicals R¹ and R² mean hydrogen atom then at least one radical of R³ and R⁴ is not hydrogen atom and methyl but other substitute, or their pharmaceutically acceptable salt. Compounds can be administrated orally for treatment of animals with convulsions. EFFECT: valuable pharmacological properties of compounds. 14 cl, 6 tbl, 3 dwg, 2 ex