FIELD: medicine, biochemistry. SUBSTANCE: invention proposes a pharmaceutical composition that can be used for inhibition of activity of 3-methyl-3-methylglutaryl-CoA-reductase in mammals. Composition has an effective amount of hesperidin or hesperetin as an active component in combination with a pharmaceutically acceptable carrier. Invention proposes also the food or drink composition designated for inhibition of activity of 3-hydroxy-3-methyl-glutaryl-CoA-reductase and containing effective amount of hesperidin and hesperetin. Composition decreases blood level cholesterol effectively. EFFECT: enhanced effectiveness of composition. 9 cl, 3 tbl, 5 ex
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