FIELD: medicine, biochemistry. SUBSTANCE: invention relates to inhibition of activity of 3-hydroxy-3-methylglutaryl-CoA-reductase in mammals. Composition has effective amount of naringin or naringenin as an active component in combination with pharmaceutically acceptable carrier. Composition can be presented as a food product or beverage containing effective amount of naringin or naringenin for inhibition of activity of 3-hydroxy-3-methylglutaryl-CoA-reductase in mammals. Composition decreases blood plasma cholesterol effectively. EFFECT: enhanced effectiveness of inhibition. 9 cl, 3 tbl
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