FIELD: hormones, pharmacy. SUBSTANCE: invention relates to gonadotropins consisting of α- and β-subunit being indicated gonadotropins contain non-native disulfide bridges, preferably, non-native intersubunit disulfide bridges. Also, invention relates to pharmaceutical compositions containing the above indicated gonadotropins. EFFECT: increased stability of gonadotropins. 12 cl, 9 dwg, 12 ex
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1998 |
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