FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, particularly a plasmid for the expression of human recombinant chorionic gonadotropin (hCG). Present invention also relates to a plasmid for the expression of individual subunits of alpha or beta recombinant human chorionic gonadotropin (hCG), a monoclonal mammalian cell line transformed with both said plasmids, and a method for producing recombinant hCG.
EFFECT: present invention provides a highly productive technology for producing recombinant human chorionic gonadotropin for biopharmaceutical production.
17 cl, 11 dwg, 4 tbl, 13 ex
| Title |
Year |
Author |
Number |
| EXPRESSION PLASMID FOR HUMAN RECOMBINANT FOLLICLE-STIMULATING HORMONE (FSH) IN CHO CELLS, EXPRESSION PLASMID FOR BETA-SUBUNIT OF HUMAN RECOMBINANT FSH IN CHO CELLS, CHO CELL PRODUCING HUMAN RECOMBINANT FSH, AND METHOD FOR PRODUCING ABOVE HORMONE |
2013 |
- Vorob'Ev Ivan Ivanovich
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Khodak Julija Aleksandrovna
|
RU2560596C2 |
| PLASMID FOR EXPRESSION OF HUMAN RECOMBINANT BLOOD CLOTTING FACTOR IX, CHO CELL PRODUCING HUMAN RECOMBINANT BLOOD CLOTTING FACTOR IX AND METHOD OF PRODUCING SAID FACTOR |
2014 |
- Kovnir Sergej Vladimirovich
- Orlova Nadezhda Aleksandrovna
- Vorobev Ivan Ivanovich
- Khodak Yuliya Vladimirovna
- Dronina Mariya Alekseevna
- Smirnov Ivan Vitalevich
- Ponomarenko Natalya Aleksandrovna
- Skryabin Konstantin Georgievich
- Gabibov Aleksandr Gabibovich
|
RU2585532C2 |
| EXPRESSION PLASMID VECTOR OF MONOCISTRONIC EXPRESSION OF RECOMBINANT PROTEINS IN MAMMALIAN CELLS, CELL LINE OF MAMMALS-PRODUCERS OF RECOMBINANT PROTEIN, METHOD OF OBTAINING RECOMBINANT PROTEIN |
2013 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
|
RU2552170C2 |
| PLASMID FOR EXPRESSION IN CELL OF CHINESE HAMSTER, CELL OF CHINESE HAMSTER - PROTEIN PRODUCER WITH Gla-DOMAIN, AND METHOD FOR OBTAINING PROTEIN WITH Gla-DOMAIN |
2013 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
|
RU2535871C1 |
| EXPRESSION PLASMID VECTOR FOR HETEROLOGICAL EXPRESSION OF RECOMBINANT PROTEINS, HIGH-FREQUENCY INTEGRATION AND AMPLIFIED AMPLIFICATION OF EXPRESSION CASSETTE IN CELLS OF MAMMALS, BICISTRONIC MESSENGER RIZIFORM, METHOD OF PRODUCTION OF STABLE LINES OF PRODUCENTS OF RECOMBINANT PROTEINS USING SPECIFIED VECTOR, METHOD FOR PRODUCTION OF RECOMBINANT PROTEINS |
2011 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
|
RU2488633C1 |
| EXPRESSION PLASMID FOR HUMAN RECOMBINANT COAGULATION FACTOR VIII WITH DELETED B-DOMAIN IN CHO CELLS, CHO CELL PRODUCING HUMAN RECOMBINANT COAGULATION FACTOR VIII WITH DELETED B-DOMAIN, AND METHOD FOR PRODUCING ABOVE FACTOR |
2013 |
- Orlova Nadezhda Aleksandrovna
- Kovnir Sergej Vladimirovich
- Vorob'Ev Ivan Ivanovich
- Vorob'Ev Andrej Ivanovich
|
RU2561466C2 |
| PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HCG (HUMAN CHORIONIC GONADOTROPIN HORMONE) |
2010 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2724528C2 |
| PHARMACEUTICAL PREPARATION CONTAINING RECOMBINANT HUMAN CHORIONIC GONADOTROPIN |
2010 |
- Cottingham Ian
- Plaksin Daniel
- White Richard Boyd
|
RU2588650C2 |
| METHOD OF PRODUCING HUMAN RECOMBINANT FOLLICLE-STIMULATING HORMONE, PRODUCING CELL LINE AND PLASMID EXPRESSION VECTORS |
2019 |
- Monakhova Varvara Sergeevna
- Klimov Nikolaj Anatolevich
- Kudling Tatyana Viktorovna
- Pigareva Natalya Vasilevna
- Karasev Maksim Mikhajlovich
- Shaldzhyan Aram Arutyunovich
- Simbirtsev Andrej Semenovich
|
RU2697273C1 |
| RECOMBINANT CHORIONIC GONADOTROPIN, A METHOD OF ITS PRODUCTION, PHARMACEUTICAL COMPOSITIONS AND THEIR USE |
2019 |
- Perez Saez, Juan Manuel
- Bussmann, Leonardo Edmundo
|
RU2803047C1 |
