Recombinant follicle-stimulating hormone (FSH), including alpha-2,3 - and alpha-2,6-sialation Russian patent published in 2021 - IPC C07K14/59 C12P21/02 A61K38/24 A61P15/08 

Abstract RU 2745557 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology, specifically to the production of recombinant FSH (follicle-stimulating hormone), including α-2,3- and α-2,6-sialation, and can be used in medicine. The resulting FSH, wherein 80% or more of the total FSH sialation is α-2,3-sialation and 5% to 20% of the total FSH sialation is α-2,6-sialation.

EFFECT: resulting FSH can be effectively used for controlled ovarian stimulation and ovulation induction in in vitro fertilization (IVF) techniques.

6 cl, 13 dwg, 11 ex

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RU 2 745 557 C1

Authors

Cottingham Ian

Plaksin Daniel

White Richard Boyd

Dates

2021-03-29Published

2018-11-08Filed