METHOD FOR PREDICTING PREMORBID STATE UNDER EXPOSURE TO CHEMICAL POLLUTANTS IN PRODUCTION ENVIRONMENT Russian patent published in 2002 - IPC

FIELD: medicine. SUBSTANCE: method involves taking venous blood and urine samples in the amount of 10 ml in the empty stomach in the morning. 0.5 ml of taken plasma (serum) is diluted with 18.5 ml of phosphate buffer solution having pH of 7.45. Chemiluminescence is induced by adding 1 ml of 50 mMole FeSO₄•7H₂O solution and measurement are taken during 10 min. Spontaneous luminescence and chemiluminescence optic sum are calculated from the moment of rash flash end to slow flash beginning. Spontaneous blood luminescence being equal to or less than 2,0•10⁵ quanta/min and greater than 7,0•10⁵ quanta/min, luminescence optic sum being equal to or less than 10,0•10⁵ quanta/min and equal to or greater than 40,0•10⁵ quanta/min and in urine spontaneous luminescence being equal to 6,0•10⁵ quanta/min or less and 12,0•10⁵ quanta/min and greater, luminescence optic sum being equal to or less than 16,0•10⁵ and equal to and greater than 70,0•10⁵ quanta/min, protective adaptation mechanism disorders are considered to take place and premorbid state development is predicted to occur. EFFECT: high accuracy and reliability of the method; simplified and accelerated examination procedure. 10 dwg, 2 tbl